Phenylacetate-coenzyme a ligase

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August undefined, 2024

WebProtein target information for Phenylacetate-coenzyme A ligase (Escherichia coli K-12). Find diseases associated with this biological target and compounds tested against it in … WebDec 25, 2001 · It is not clear whether the release of the coenzyme A moiety requires an extra enzyme. ... In the related bacterium A. evansii sequencing of the genes next to the gene for phenylacetate-CoA ligase revealed three open reading frames that are transcribed in the same direction and which are separated by only short intergenic regions. The ...

Biochemical and Molecular Characterization of …

WebJul 21, 2010 · Proposed enzyme names : 1: phenylacetate-CoA ligase (AMP forming); 2: ring 1,2-phenylacetyl-CoA epoxidase (NADPH); 3: ring 1,2-epoxyphenylacetyl-CoA isomerase … WebDec 27, 2012 · In the lower pathway, phenylacetate is ligated to coenzyme A to produce phenylacetyl coA, and then split by several enzymes to produce acetyl coA, which enters the TCA cycle. Catabolic enzymes The upper pathway enzymes are encoded by the styABCD operon in strains of Pseudomonas and Rhodococcus . robert leiner visions of the past

Phenylacetate-coenzyme A ligase is induced during …

WebSep 28, 2024 · Phthalate esters are a class of refractory synthetic organic compounds which are widely used in plastics, coatings, and for several industrial applications such as packaging, pharmaceuticals,... WebPhenylacetate-CoA ligase (E.C. 6.2.1.30), the initial enzyme in the metabolism of phenylacetate, was studied in Thermus thermophilus strain HB27. Enzymatic activity was upregulated during growth on phenylacetate or phenylalanine. The phenylacetate-CoA ligase gene (paaK) was cloned and heterologous ... >> More Curr. Web258 rows · Phenylacetate-coenzyme A ligase PaaK, adenylate-forming domain family: 1099: 1224: COG1546: H Nicotinamide mononucleotide (NMN) deamidase PncC: 86: 86: … robert lenderman obituary

phenylacetate + Coenzyme A + ATP => phenylacetyl-CoA - Reactome

WebJun 1, 1993 · Phenylacetate-CoA ligase (AMP forming) was found in cells grown anaerobically with phenylacetate and nitrate. Maximal specific enzyme activity was 0.048 … WebOct 1, 2005 · abstract. Three phenylacyl-CoA ligase activities were detected in extracts of Pseudomonas putida CA-3 cells grown with a variety of aromatic carboxylic acids. The three phenylacyl-CoA enzyme activities measured were phenylpropyl-CoA ligase (acting on both phenylpropanoic acid and cinnamic acid), a phenylacetyl-CoA ligase, and a medium chain … robert lenard neapcoWebIt catalyses the reaction phenylacetate + CoA + ATP --+ phenylacetyl-CoA + AMP § PPi and requires Mg 2+. Phenylacetate-CoA ligase (AMP forming) was found in cells grown … robert leithman new orleans

"WebABSTRACT. Phenylacetate-coenzyme A ligase (PA-CoA ligase; AMP forming, EC 6.2.1.30 ), the enzyme catalyzing the first step in the aerobic degradation of phenylacetate (PA) in … " - Phenylacetate-coenzyme a ligase

Phenylacetate-coenzyme a ligase

Bacterial phenylalanine and phenylacetate catabolic …

WebPhenylacetate-CoA ligase (E.C. 6.2.1.30), the initial enzyme in the metabolism of phenylacetate, was studied in Thermus thermophilus strain HB27. Enzymatic activity … WebNov 1, 2008 · The phl gene, encoding a PCL (phenylacetate–CoA ligase), was cloned in Escherichia coli as a maltose-binding protein fusion and the biochemical properties of the enzyme were characterized. The...

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WebJun 1, 1993 · Anaerobic degradation of (4-hydroxy)phenylacetate in denitrifying Pseudomonas sp. was investigated. Evidence is presented for α-oxidation of the coenzyme A (CoA)-activated carboxymethyl side chain, a reaction which has not been described. The C6−C2 compounds are degraded to benzoyl-CoA and furtheron to CO2 via the following … WebCatalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

WebCatalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). WebKEGG Orthology (KO) [BR:lbx00001] 09100 Metabolism 09105 Amino acid metabolism 00360 Phenylalanine metabolism lbkm_0810 Enzymes [BR:lbx01000] 6. Ligases 6.2 Forming carbon-sulfur bonds

WebAug 10, 2010 · Intermediates are processed as CoA thioesters, and the aromatic ring of phenylacetyl-CoA becomes activated to a ring 1,2-epoxide by a distinct multicomponent oxygenase. The reactive nonaromatic... WebIn enzymology, a phenylacetate-CoA ligase is an enzyme that catalyzes the chemical reaction. The 3 substrates of this enzyme are ATP, phenylacetate, and CoA, whereas its 3 …

WebDec 25, 2001 · In the denitrifying bacterium Thauera aromatica phenylacetate is oxid... Phenylacetyl‐CoA:acceptor oxidoreductase, a membrane‐bound molybdenum–iron–sulfur enzyme involved in anaerobic metabolism of phenylalanine in the denitrifying bacterium Thauera aromatica - Rhee - 1999 - European Journal of Biochemistry - Wiley Online Library

WebPhenylacetate-coenzyme A ligase EC number EC:6.2.1.30 ( UniProtKB ENZYME Rhea) 1 publication Alternative names Phenylacetyl-CoA ligase ( PA-CoA ligase) Gene names … robert lemon chatfield deanWebMar 1, 1993 · Evidence is presented that in all the isolates as well as in four previously isolated control strains with the ability to utilize phenylacetic acid, the enzyme … robert leniart restorationWebCatalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). robert lenahan architectWebThe ligase is active as a monomer of molecular mass 48 kDa, as determined by gel filtration and SDS/PAGE. At a pH optimum of 8.5, the apparent Km values for 4-hydroxybenzoate, ATP, and coenzyme A are 37 μM, 77 μM, and 125 μM, respectively. The enzyme reacts specifically with 4-hydroxybenzoate (100%) and 4-aminobenzoate (30%). robert leith w mifflin pa robert lenoil ins. agencyWebFold: Names of enzymes and/or genes present: Phenylacetate-CoA ligase paaK. EC numbers: 6.2.1.30 (Phenylacetate-CoA ligase) Catalytic residues: Notes: Numbers [P] (Evidence at Pro robert leo obituaryWebPhenylacetate-coenzyme A ligase EC number EC:6.2.1.30 ( UniProtKB ENZYME Rhea) Alternative names Phenylacetyl-CoA ligase ( PA-CoA ligase) Gene names Name paaK … robert lenkiewicz paintings for sale